Eastern Jilin Heilongjiang provinces have become the most important areas to exploration in the future, with the constant emergence of prospecting progress and assessment results, and systematic study on metallogenic planning and exploration deployment are on demand. Based on the prospecting progress and assessment results, this study confirmed a new metallogenic belt, revised its boundary and named it the Jiheidong Jilin Heilongjiang Au-Ag-Cu-Mo metallogenic belt. Combined with the analysis about regional geology setting, we divided the study area into three III grade belts, and preliminarilyy established the metallogenic pdigree of this metallogenic belt based on the previous work. The mineralization in this area is characterized by multi phase and multisystem, and the show multi cycle, inheritance, and superimposition in the time evolution sequence.The Hercynian and The late Indosinian Yanshanian were the metallogenic outbreak period. The main metallogenic types in study area are: sedimentary metamorphic graphite-Fe-Au deposit, marine volcano gas hydrothermal Cu-Pb-Zn polymetallic deposit, contact metasomatic magmatic hydrothermal polymetallic deposit, and magmatic copper Nickel deposit. Bedides, this research also determined 13 prospect areas in eastern Jilin Heilongjiang provinces Au-Ag-Cu-Mo Metallogenic belt and 7 of those are the key areas, and this work may guide the next exploration deployment work effectively.