The basic granulites in the central Himalaya provide insights into the tectonic evolutionary history of both the pre- Himalayan of the Indian continent and the Himalayan collisional orogeny in the Cenozoic. Here, we conduct a petrological, bulk rock major- trace geochemical and zircon U- Pb geochronological study on the garnet amphibolites in the Duoqinghu of Yadong area, revealing their protoliths and Cenozoic metamorphism. The protoliths of the garnet amphibolites are probably the Neoproterozoic (~890 Ma) basalt with E- MORB geochemical characteristics. The garnet amphibolites have three- stage mineral assemblages. The early prograde metamorphic mineral assemblage is garnet+amphibole+plagioclase+ilmenite+quartz, which includes the core of garnet and inclusions within the core of garnet porphyroclast. The peak metamorphic mineral assemblage is garnet+amphibole+plagioclase+biotite+quartz, including the garnet rim and matrix minerals. The retrograde metamorphic mineral assemblage is amphibole+orthopyroxene+plagioclase+biotite+quartz, which is represented by the symplectitic minerals surrounding the garnet rim and retrograde domain. Conventional thermobarometry and phase equilibria modeling show that the prograde, peak and retrograde metamorphic conditions of garnet amphibolites are 609~621℃ and 0. 59~0. 65 GPa, 805~845℃ and 0. 91~1. 04 GPa, and 825~840℃ and 0. 61~0. 68 GPa, indicating that the garnet amphibolites have experienced peak high pressure and high temperature granulite- facies metamorphism. The zircon U- Pb geochronology shows that the peak and retrograde metamorphic ages of garnet amphibolites are 34. 8~20. 3 Ma and 18. 1~17. 7 Ma, indicating a prolonged melting episode. These results show that the garnet amphibolites are products formed during the long- lived subduction and crustal thickening of the Indian continental crust beneath the Euro- Asian plate, and their protoliths may be related to the Rodinia supercontinent convergence event. The clockwise P- T path of garnet amphibolites characterized by the burial heating and then near isothermal decompression indicates that the upper structural level of the Greater Himalayan Sequence (GHS) in the central Himalaya experienced long- lived crustal thickening and high- temperature granulite- facies metamorphism. Moreover, the upper structural level of the GHS uplifted at a relatively rapid rate (3. 0~4. 5 mm/a) in the early Miocene at ca. 21~17 Ma, but a relatively slower rate (1. 1~1. 3 mm/a) after 17 Ma.