Located in Luanchuan metallogenic concentration area in the southern margin of north China Craton, the Luotuoshan sulfide polymetallic deposit is a large- scale non- ferrous metal deposit mainly composed of sulfur and zinc, accompanied by abundant In, Cd and other resources. In this paper, indium is taken as the key research object. Based on detailed field geological survey and microscopic observation, ICP- MS, LA- ICP- MS and other analysis and test methods are applied to study the contents, distribution characteristics and correlation of In, Zn, Sn, Cd, Cu and other elements in different types of surrounding rocks, ores and different minerals of Luoshuoshan deposit. It aims to reveal the distribution and enrichment rule of indium. The results show that the hornite and skarn of Luotuoshan deposit have high background value of In, which mainly occurs in marmatite (average 276. 8×10-6) and chalcopyrite (average 117. 7×10-6) in the form of isomorphism, which is closely related to the dense massive ore (average 63. 9×10-6). Like other ore- forming materials, In may mainly comes from the deep magma, and its vertical distribution shows that the content of In in near skarn area is higher than that in areas distant from skarn area, and its enrichment degree is obviously controlled by temperature. The concentration of In in the ore was positively correlated with Zn, Cu, Cd, but not with Sn. In in marmatite was positively correlated with Zn, Cu, Cd contents, while In in chalcopyrite shows a weak positive correlation with Zn and Sn contents, the enrichment and replacement mechanism of In in chalcopyrite needs to be further studied.