The Kaerqueka copper- polymetal deposit is one of the most important copper polymetallic deposits in the Qimantage metallogenic belt. This deposit is divided into three mining areas: A, B and C. This polymetallic deposit is mainly composed of copper, lead and zinc, accompanied by iron, gold and silver mineralization. In this paper, the chemical composition characteristics of chalcopyrite, pyrite, magnetite, sphalerite and bornite are analyzed. Based on S element content and (Fe+Cu)/S ratio (mean values are 1. 93, 1. 82, 1. 8, respectively) of chalcopyrite, Co/Ni value (mean values are 5. 43, 3. 89, 1. 06, respectively) of pyrite, Fe content and Zn/Cd ratio (area B and area C have Zn/Cd ratio between 177. 84~488. 13) of sphalerite. Combined with the characteristics of pre- induced fluid inclusion temperature measurement, the mineralization temperature of Kaerqueka deposit was determined as zone A＞zone B＞zone C, in which zone B no. 7 vein＞no. 8 vein＞no. 4 vein. Zone A was mineralized in medium- high temperature environment, and zone B and C were formed in the early stage of middle and high temperature and in the late stage of middle temperature. Using Co, Ni, As element characteristics in pyrite, Cd, Zn, Mn and Fe element characteristics in sphalerite, combined with the metallogenic environment of mining area (areas A, B, C), and geological characteristics of ore deposits, it is shown that area A of the Kaerqueka deposit has the genetic characteristics of porphyry copper deposit controlled by magmatic hydrothermal fluid; and area B and C have the genetic characteristics of skarn deposit.