In this paper, we employ the back- slip dislocation model to invert the distribution of fault coupling and slip rate deficit on the different segments of the Tanlu fault zone, according to the GPS- derived horizontal velocity field data of 1999~2007 and 2013~2017 in North China. Combining the deformation characteristics following the two periods, we discuss the possible relationship between the deformation characteristics with the Japan 3·11 Tohoku earthquake. The results show that the coupling rate reduces in the north of Tancheng County on the middle- south segments of the fault following the earthquake; and meanwhile the principal extensional strain rate increases in the eastern part, suggesting the strain release in the middle and south segments following the earthquake. The inversion derived from the 2013~2017 data shows that the north segment of Juxian still has the high coupling rate, the deep blocking depth, and the dextral compressive deficit, which is the unrupture section of the 1668 Tancheng earthquake. The coupling rate is low from south of Juxian County to the vicinity of Sihong, and there is no slip deficit accumulation. From south of the Sihong to Jiashan segment, the coupling rate is higher, which is the unrupture section of the Tancheng earthquake. More importantly, the seismic hazard should pay more attention as the sparse micro- seismicity, which is beneficial to accumulate the stress.