The ore- bearing rock series of bauxite deposit in the Wuchuan- Zheng’an- Daozhen (WZD) area in northern Guizhou consists of lower Permian Dazhuyuan Formation, underlying lower Silurian Hanjiadian Formation or upper Carboniferous Huanglong Formation, and overlying middle Permian Liangshan Formation, three of which are in discordant contact. The paleosedimentary environment was mainly shallow lacustrine facies and the genesis of the deposit belongs to the sedimentary type of ancient weathering crust. Exploration and research show: (1) All the Al- bearing rock series are rich in Li, Ga, Sc, REE, etc., and vary greatly in spatial distribution and contents of different ores by 1~3 orders of magnitude. Lithium content is relatively high in the east and west sides of the study area. Li is concentrated in the upper part of the ore- bearing rock series and orebodies in massive and oolitic shapes. Ga is relatively enriched in the north of the study area and ore- bearing rock series. Sc is highly enriched in the Daozhenshaba- Pingmushan area and has little changes in content. REEs are relatively concentrated in the south and significantly in the lower part of ore- bearing rock series. (2) The ore- bearing rock series formed near the ancient equator in an open oxidized environment with warm and humid climate. Al- bearing minerals and Al- rich clay minerals (kaolinite and smectite) are abundant, promoting the migration and enrichment of Li, Ga, Sc and REE in the form of ion adsorption along with the mineralization process of desiliconization, iron removal and sulfur reduction of bauxite. At the same time, Li, Ga, Sc, REE and other rare elements have similar ionic radius and geochemical properties as the lithotropic elements (Al, Zr, Ti, Nb, Ta, Hf, Ti, Cr, Th, U), and isomorphism may occur partially in the process of bauxite mineralization. (3) Secondary leaching modification and environmental pH changing are important factors to promote the formation of independent rare earth minerals and the enrichment of REEs at the bottom of ore- bearing rock series. A large amount of rare earth layers may occur at the bottom of ore- bearing rock series as independent minerals (especially in the section of REE>800×10-6). The uneven distribution of Li, Ga, Sc and REEs were restricted by paleosedimentary environment, topography and geomorphology and tectonic movement after diagenesis and mineralization. (4) With Al- bearing rock series as the evaluation object, this study suggests that Li, Ga and Sc in the study area are of great resource potential and huge economic value.