Cretaceous uplifting – exhumation process is widely developed in different tectonic units in Xinjiang. Apatite Fission tract dating and thermal history modeling have been carried out from 17 granite samples collected from Boluokelu mountain, Yilianhabierga mountain and Duku road to investigate the uplifting – exhumation processes of mountains. The research area include north part and middle part of western Tianshan. Fission – track ages for these samples range from （81.6±4.9）to（45.4±3.2）Ma with mean track lengths varying from （12.62±0.17） to (13.53±0.14) μm. Temperature – Time modeling of apatite was completed based on date measurements of the fission track length and age. Analyses results revealed that the north part and middle part of western Tianshan has probably experienced rapid cooling events on late Cretaceous. The time for rapid cooling events on north part of west Tianshan mainly concentrated during 50 ~ 70Ma, and the time for middle part of west Tianshan mainly concentrated during 70 ~90Ma. In combination with other geological evidence, it is suggested that the western Tianshan appear differential uplift and exhumation process in late Cretaceous. This event can be controlled by multi – factor. The distant effect of the India – Asia collision is the dynamical source. The main control factor are related to the thermal – rheological structures and different structural boundaries interaction.