A suit of amphibolites facies meta-sedimentary rocks outcrops at Qinghai Nanshan area. It has been previously considered to be comparable with Jinshuikou Group in the East Kunlun orogenic belt, but its formation age and tectonic attributes are still quarreled. We present new results from zircon U-Pb and Lu-Hf isotopic data on sillimanite-mica-quartz schist and granitic pegmatite pluton. Detrital zircon grains from sillimanite-mica-quartz schist yield a U-Pb main peak at~779Ma with εHf(t) values of -23.7~-11.8 and TDM2 ages of 2436-3172Ma, which is extraordinarily younger than Jinshuikou Group with detrital zircon ages older than 1.9Ga. Several Paleoproterozoic-Archean (1744-2819Ma) detrital zircon grains are also gotten. These detrital zircon ages are concordant with Proterozoic meta-sedimentary rocks in Danghe Nanshan and Hualong areas of the South Qilian belt. The ~779Ma detrital zircons ages are identical with the Neoproterozoic magmatism in Central Qilian and South Qilian belts. The S-type Granitic pegmatite was formed at 439±2Ma in the subduction-related setting. Magmatic zircons have ɛHf(t) values of -14.2~-7.7, evolved from recycled Paleoproterozoic crustal. Inherited zircon with 775Ma is identical with the peak age of detrital zircons from sillimanite-mica-quartz schist, indicating that the latter contributes to the granitic pegmatite magma. Thus, the zircon U-Pb analysis results constrain meta-sedimentary rocks from Qinghai Nanshan area is formed between 779Ma to 439Ma, dominated by sediments from ~779Ma magmatic source. They possess similar sediment sources and tectonic attributes with contemporary meta-sedimentary rocks in Danghe Nanshan and Hualong areas of the South Qilian belt.