There are giant gold deposits such as Muruntau, Kumtor and Kalmakyr, world-class copper deposits such as Kalmakyr and Dal’neye, and super-large zinc-lead deposits such as Tekeli in western Tianshan forming a giant Au-Cu-Zn-Pb metallogenic belt, attracting the attention from the world. Yet it is hoped to find gold, copper and zinc-lead deposits significantly in Xinjiang western Tianshan, China. It is necessary to continuously understand the tectonic-metallogenic processes of total western Tianshan from Uzbekistan, Kylgyzstan, through south-eastern Kazakhstan to western Xinjiang, China, confirm the survey direction and predicte large ore clusters in western Tianshan. Through a wide survey of regional geology and ore deposits in western Tianshan and synthetic study of references, we suggest that the western Tianshan orogenic belt experienced four geological processes, they were Precambrian continent marginal basin, Paleozoic ocean-continent subduction accretion, Later Paleozoic continent-continent collision orogeny and Mesozoic- Cenozoic depression basin. Accordingly, there were forming four metallogenic systems and types of: ①Proterozoic marginal basin Zn-Pb system and SEDEX-type, ②Paleozoic subduction arc Au-Cu-Zn-Pb system and porphyry-, skarn-, and epithermal-types, ③Later Paleozoic collision orogenic Au-Zn-Pb system and orogenic-tpye and MVT, ④Mesozoic-Cenozoic depression Zn-Pb-Cu system and sandstone-type. Based on the synthetic comparission of the metallogenic systems developing in western Tianshan at home and abroad, it is predicted that Nalati-Enlbin centre Tianshan rise zone is very important to find orogenic gold deposits, the Tulasu basin, Bayinbuluk centre Tianshan and northern margin of Nalati are hoped to find porphyry gold-copper deposits, the new SEDEX-type of zinc and lead deposits would be find in Proterozoic systems in southern margin of Yili block, and the Mesozoic-Cenozoic depression basin in or in front of western Tianshan is certainly the first choice to find the sandstone-type of Zn-Pb-Cu deposits.