The Liucun intrusion locates in the south of Anhui province where is the junction of Anji county in Zhejiang and Guangde county in Anhui. Main constitution of the intrusion is the fine-coarse porphyritic monzogranite with colour of light to pinkish red. The intrusion invaded from the anticlinal axis composed of Cambrian strata. Liucun monzogranite is the approach-aluminous to peraluminous A-type granite with the features of high-potassium, alkali-rich and low-Mg#. The rare earth element chondrite-normalized distribution pattern leans to the right obviously, and has deep europium valley. The spider diagram of the primitive mantle-normalized trace element curves have obviously negative Ti and Sr anomalies leaning to right. Overall，the intrusion has low HFSE and high LILE. Characteristics of major and trace element indicate that the magma formed the Liucun monzogranite came from lithospheric mantle and contaminated by continent crust. The process of magmatic evolution had occurred crystallization and differentiation of the minerals of apatite, hornblende, pyroxene, titanite and so on. Liucun monzogranite was dated to be 132.84±0.57 Ma by LA-ICP-MS zircon U-Pb method, which belongs to early Cretaceous. It is the second stage magmatic movement of Yanshanian in southern Anhui province. Liucun monzogranite formed at the transfering period of the structure activation and tectonic mechanism converting from compression to extension in late Jurassic to early Cretaceous。This area is favourable for prospecting gold, silver, tungsten-molybdenum polymetallic deposits because of its obvious geochemical gold anomalies.