Northeast Guangxi has a unique tectonic unit, and is located between the Jiangnan orogenic belt and the South China fold belt. The paper presents the accurate ages of a series of deposits and their related granites with zircon SHRIMP U-Pb, zircon LA-ICP-MS, and the muscovite and biotite Ar-Ar, as well as the molybdenite Re-Os methods. On the basis of deposit types, mineralized elements assembleges in the region, The deposits could be divided into six ore-forming system, namely, (1) W-Mo deposits related to Silurian granite; (2) Sn-Nb-Ta deposits related to late Triassic granite; (3) W-Mo deposits associated with Triassic granite; (4) W-Sn deposits related to Middle-Late Jurassic granite; (5) W-Sn deposits associated with Cretaceous granite; (6) Uranium deposit related to Indosinian granite. The formation of these deposits is closely related to the different periods of tectonic-magmatic evolution, and associated with the syn-collision compressional setting and/or post-collision extensional setting.