Kaerqueka is located in Qinghai Province,Qimantage area within the western part of East Kunlun Mountains, further ore-prospecting potential is tremendous. This research reveals the temperature of inclusions and discusses the causes of fluid inclusions.And this research indicates the chemical composition and genesis of fluid through the analysis of Raman and the method of hydrogen and oxygen isotopic composition, And on this basis explores the relationship of fluid between the Kaerqueka porphyry mineralized zone and skarn mineralized zone. The results of researching on inclusions suggest that the metallogenetic fluid consists of high-temperature，hypersaline fluids and medium-low temperature，low salinity ones in porphyry mineralized zone and skarn mineralized zone. The stage of sericite alteration is the main metallogenic stage in porphyry mineralized zone,and the homogeneous temperature region is 260~400℃. homogeneous temperature region of wet skarns phase in skarn deposit is 260~400℃, and this period is the main stage of metallogenic materials precipitation.both homogeneous temperature of mineralization stage are matched. And each homogeneous temperature region correspond well. Through the research on the hydrogen and oxygen isotopic composition of the inclusions, the metallogenic fluid of Kaerqueka porphyry mineralized zone and skarn mineralized zone are derived from the magma water.but the fluid of porphyry mineralized zone compounds of atmospheric precipitation with the obvious \"d18O moves\" phenomenon.The esults of Raman probe analysis show that metallogenic fluid of Kaerqueka mining areas is a complicated system which is a mainly set of H2O-CO2-NaCl-CH4 and contains faintly H2S and N2.Kaerqueka porphyry mineralized zone and skarn mineralized zone belong to the same metallogenic series which is porphyry-skarns copper molybdenum lead iron metal metallogenic series were caused by collision and post extensionin in acidic magma activities.