The MiddleLower Reaches of Yangtze River is a well-known Mesozoic metallogenic belt in central eastern China, which has been the key base of mineral supply for the Yangtze industry corridor, and then is nicknamed The Industry Cradle. In view of geological evolution and metallogenic dynamics, the MiddleLower Yangtze metallogenic belt has its own distinguishing features in China, even in the world. Firstly, the tectonic background and processes had experienced the environments from plate margin to intraplate during T2-J2, and mineralization occurred in transformation from compression to extension (145~130 Ma). Secondly, diagenesis and mineralization in the belt were controlled by base structure and deep process, and related to its own basement. In conclusion, the MiddleLower Yangtze mineralization had occurred through the whole Yanshanian epoch (165～120Ma) and distinctly recorded the imprint of subduction of Pacific Plate during Late Jurassic to Early Cretaceous.