Abstract:The REE content of rocks and ores range widely in Yindongzi AgPb polymetallic deposit, REE distribution patterns dip to right, enrich LREE, and differentiates pooly for HREE, barite vein and ores have negative Ce anomaly, the depletion of Ce imply submarine hydrothermal process. The composition of S isotope has wide range in Yindongzi AgPb polymetallic deposit, heavy S isotope predominates, δ34S value of main orebody orebear solution is similar with that of Devonian sea water, it indicate that sulfur derived form Devonian sea water in semienclosed reducing condition. Pb isotope analysis suggested that Pb mainly came from depth, related with volcanic activity in sea floor. It showed that the deposit formed in Middle Devonian era, and metallogensis happened simultaneously with hydrothermal sedimentary rockforming process by isotopic date references and geologic study. It proved that hydrothermal sedimentary process was main oreforming means by research. It proposed that the formation of this deposit divided into two stages, included submarine exhalation sedimentary oreforming and reformed metallogensis stages, the former dominated and formed hydrothermal sedimentary rocks (baritic rock and silica rock, and so on) and fine metal minerals. The metallogenic model of this deposit is built, too. Combined with geological exploration work in ZhaShan region, it summed up five prospecting criteria and took exploration prediction in surrounding ore field and new region, and delineated eight predicting targets by studying and analyzing relative references. These conclusion pointed direction for probing further mineralization mechanics and exploring in ZhashuiShanyang sedimentary basin.