In the south Three Rivers region, the geologic-tectonic evolution was complex. There was multi-stages mineralization during evolution of paleo-tethys and inner continental convergent orogeny,. but the involved spatial scope was different. regional metallogenic regulation couldn’t be reflected clearly by the unified division of metallogenic belts. According to the tectonic cycles, such as precambrian, paleo-tethys and continental orogenic cycle, the metallogenic belts were divided. new division scheme was proposed in this paper. From the middle-south area of three river to southeast asia, there should be 5 large metallogenic belts extending over 1000 Km: Cu, Ni, PGE metallogenic belt of Dali-Ailaoshan, Pb-Zn, Ag-Cu-Co, Hg-Sb polymetallic metallogenic belt of Lanping-Simao, western and middle Sn metallogenic belt of southeast asia. In addition, a lot of geological problems about metallogenic belts were also discussed.