Abstract:The Yazigou polymetallic deposit, discovered recently by the Qinghai Geological Survey in the Qimantage area of East Kunlun Mountain, Qinghai Province, is characterized by porphyrytype mineralization. The authors have conducted geochronological study on the samples from the orebearing porphyry and orebodies by SHRIMP zircon UPb and molybdenite ReOs dating, respectively. The zircon UPb age for the Kfeldspar granitic porphyry is 224±1.6 Ma while the ReOs age of ore molybdenite is 224.7±3.4 Ma, suggesting that diagenesis and mineralization took place coevally with the intense crustmantle interaction in the East Kunlun orogenic belt in Late Indosinian. Meanwhile, the interaction between crust and mantle resulted in largescale magmatichydrothermal activities and metallogeny. The Kfeldspar granitic porphyry is closely related to polymetallic mineralization and the mantlederived diorite, diabase and gabbro in the area both temporally and spatially. It is refered that that the magmatic intrusives mentioned above are all the products of the crustmantle interaction. Based on the geochronological study, it is proposed that the Yazigou deposit has the same geodynamical setting as the whole Eastern Kunlun orogenic belt in Late Indosinian. Meanwhile, the authors also point out that there are good potentials for porphyry deposit prospecting in the area.