The Xilikuduke area in northern Xinjiang is a porphyry copper-molybdenum-gold deposit.Ore-hosted granodiorite in the area commonly contains four types of melanocratic microgranular enclaves(MME) such as aphanitic andesite-basalt,granule diorite,porphyritic andesite and andesitic porphyrite.There still occur some dykes like andesitic porphyrite,dacitic andesitic porphyry and syenite in the ore district.Lithology,mineral chemistry and lithogeochemistry of granodiorite and its enclaves indicate that there exists magma mixing in this area and that mixing between acid granodiorite magma and basic diorite magma has produced transitional facies-andesitic porphyrite magmatic mixed rock.Mineralization is related to MME,which is supported by following evidence:the more intensive mineralization,the more number of MME;magnetite,and even pyrite and chalcopyrite commonly exists in some enclaves.Lithogeochemistry reveals that the magmatic mixed rock,i.e.andesitic porphyrite,shares similar geochemistry with altered-mineralized granodiorite,e.g.close plot area on the Harker diagram and similar REE and trace elements patterns in chondrite-and primitive mantle-normalized diagrams,which suggests that the two rocks might have similar genesis.In other words,the hydrothermal alteration and mineralization possibly accompanied with magma mixing.It is deduced that the magma mixing in this area may result from the mixing of mantle-source mafic magma and continental-source granitoid magma,and that the Cu-Au mineralization in this area may be derived from the magmatic differentiation and magmatic hydrothermalism of the intermediate to acid mixed magma.