According to the spatio-temporal and genetic relationships between the Mo, (W), Au, Ag, Pb, Zn deposits and related magmatic intrusive bodies in east Qinling-Dabie mountains, these deposits are classified to a minerogenetic series related to Mesozoic magmatic activities and furthermore divided into four minerogenetic sub-series: the Mo, REE minerogentic sub-series related to middle-late Triassic alkaline magmatic activities, the Mo (W), Ag, Pb, Zn, (Au) minerogenetic sub-series related to late Jurassic-early Cretaceous I-type granitic porphyry, the Au minerogenetic sub-series related to early Cretaceous S-type granitic batholith, and the Mo, Pb, Zn minerogenetic series related to the late stage of early Cretaceous A-type granitic porphyry. The tectonic setting, related magmatic activities and mineral suits exhibits a regular spatio-temporal evolution.