The sericite-adularia type epithermal Ag-Au deposit, acid-sulfate type Cu-Au epithermal deposit and porphyry type Cu(Mo) deposit constitute an intrusion-centered hydrothermal system in the Zijinshan region. The porphyry Cu(Mo) deposit was related to the magmatic high-salinity and high-temperature fluid developed at the top of granodiorite porphyry. The acid-sulfate type Cu-Au epithermal deposit was formed by precipitation of an acid, low-salinity and low-temperature hydrothermal fluid, which was near the magmatic source, formed after reformed porphyry copper and carrying magmatic volatiles. The sericite-adularia type epithermal Ag-Au deposit was a product of a neutral or slightly acid, low-salinity and low-temperature hydrothermal fluid, which was laterally heated up by a granodiorite porphyry intrusion and laterally flowing.