The Silk Road Economic Belt and the 21st-Century Maritime Silk Road Initiative, abbreviated as the Belt and Road Initiative, is a primary development strategy of China’s future international cooperation. Especially, the energy resource cooperation, including oil and gas resources cooperation, is an important part of this initiative. The Belt and Road has undergone complicated geological evolution, and contains abundant mineral resources such as oil, gas, coal, uranium, iron, copper, gold and manganese ore resources. Among these, Africa holds 7.8% of the world’s total proven oil reserves. The oil and gas resources in Africa are relatively concentrated, with an overall low exploration degree and small consumption demand. Nigeria and Libya contain the most abundant oil resources in Africa, accounting for 2.2% and 2.9% of the world’s total reserves, respectively. Nigeria and Algeria hold the richest natural gas resources in Africa, occupying 2.8% and 2.4% of the world’s total reserves, respectively. Africa’s oil and gas resources are mainly concentrated in Egypt, Sultan and Western Sahara regions in the northern Africa, and the Gulf of Guinea, Niger River and Congo River area in the western Africa. The Russia–Central Asia area holds rich petroleum resources in Russia, Kazakhstan, Turkmenistan and Uzbekistan. The potential oil and gas areas include the West Siberia Basin, East Siberia Basin and sea continental shelf in Russia, the northern and central Caspian Basin in Kazakhstan, the right bank of the Amu-Darya Basin, the East Karakum uplift and the South Caspian Basin in Turkmenistan, and the Amu–Daria Basin, Fergana Basin, Afghan–Tajik Basin and North Ustyurt Basin in Uzbekistan. The Middle East oil and gas resources are mainly distributed in the Zagros foreland basin and Arabian continental margin basin, and the main oil-producing countries include Saudi Arabia, Iran and Iraq. The Asia Pacific region is a new oil and gas consumption center, with rapid growth of oil and gas demand. In 2012, this region consumed about 33.6% of the world’s total oil consumption and 18.9% of the world’s total natural gas consumption, which has been ranked the world’s largest oil and gas consumption center. The oil and gas resources are concentrated in China, Indosinian, Malaysia, Australia and India. The abundant European proven crude oil reserves are in Norway, Britain and Denmark and also rich natural gas resources in Norway, Holland and Britain. Norway and Britain contain about 77.5% of European proven oil reserves, which accounts for only 0.9% of the world’s proven reserves. The Europe includes main petroliferous basins of the Voring Basin, Anglo–Dutch Basin, Northwest German Basin, Northeast German–Polish Basin and Carpathian Basin. According to the analysis of source rocks, reservoir rocks, cap rocks and traps for the main petroliferous basins, the potential oil and gas prospecting targets in the Belt and Road are mainly the Zagros Basin and Arabic Platform in the Middle East, the East Barents Sea Basin and the East Siberia Basin in Russia–Central Asia, the Niger Delta Basin, East African rift system and the Australia Northwest Shelf. With the development of oil and gas theory and exploration technology, unconventional petroleum resources will play an increasingly important role in oil and gas industry.