In recent years, chromium (Cr) isotope systematics have been widely used in tracing geological processes related to mantle partial melting, magma differentiation, and subduction fluidrelated processes. This study summarizes the main advances in using Cr isotope geochemistry in chromite deposits in maficultramafic rocks, including: ① Cr isotope compositions of chromite and coexisting silicates in the peridotite zone of the Stillwater complex and crustmantle transition zone of the Kzlda AgˇGophiolite reveal that Cr isotopes had been significantly fractionated during formation of both stratiform and stratiformlike chromitite, which was mainly controlled by fractional crystallization and magma replenishment; ② Cr isotope compositions of the podiform chromitite from Kzlda AgˇG ophiolite suggested that spinel in the mantle peridotites in the subduction zone is one of the mainly Cr sources in podiform chromitite, and the subduction zone fluids may also directly participate in mineralized formation; ③ diffusiondriven intermineral Cr isotope fractionation in ophiolite and layered intrusion can not only be used to estimate cooling time of magmas, but also reveal critical medium role of hydrous fluids in chemical exchange between minerals.