Serpentine, with a water content of about 13%, is an important hydrated mineral on the earth and widely distributed in different tectonic environments, e.g., the ocean floor, subduction zones and fore-arcs. Except fluids, fluid-mobile elements (B, Li, As, Sb, Pb, Cs, U, Sr, Ba) can be also enriched in serpentine with serpentinization. Thus, serpentine can be present as the important host for fluids and these elements in different geological processes. However, different tectonic environments have varying temperatures and pressures with potentially different properties of fluids. Serpentinization in different environments cannot only result in the formation of different serpentines (e.g., lizardite, antigorite), but may also lead to different enriched characteristics of serpentine, which require further studies. Based on comparison of compiled literature data for serpentinite produced in different tectonic environments worldwide, together with the serpentinite samples from two typical orogenic belts of Southwest Tianshan and Qilian Mountains, we found that abyssal serpentinite and serpentinite in subduction zones show different enriched characteristics of B, Ba and Cs : (1) abyssal serpentinite has significantly higher B contents, which may reflect the preference of B to serpentinite at lower temperature; (2) Ba and Cs contents of serpentinite formed in subduction zones are relatively higher, which may indicate tbe contribution of subducting sediments. This conclusion is helpful for interpreting the tectonic environment for serpentinite through its compositional characteristics.