Manyporphyry- skarn type polymetallic deposits are developed in Middle and Lower Yangtze River Valley metallogenic belt. However, the lack of accurate mineralization chronologic data severely restricts in- depth understanding of the genesis and geodynamic setting of these deposits. The Tongjiangling Cu- W deposit is a newly discovered porphyry- skarn deposit, which is located in the north part of the Jiujiang- Ruichang ore concentration area of the Middle and Lower Yangtze River metallogenic belt. Chalcopyrite and scheelite are the common metal minerals, occurring as veins and disseminations in the granodiorite porphyry and skarn. In this paper, the authors have undertaken LA- ICP- MS U- Pb dating of garnet in ore- bearing skarn and zircon in granodiorite to define the mineralization age of this deposit. The U- Pb LA- ICP- MS dating of zircons from Tongjiangling granite porphyry yielded an age of 146.3±0.9 Ma (2σ, MSWD=1.13, n=33). LA- ICP- MS U- Pb dating of garnets from skarn yield weighted mean 206Pb/238U age of 142. 9±2. 1 Ma (2σ, MSWD=1. 2, n=17), indicating consistent diagenetic and metallogenic ages and their close genetic relationship. These data indicate that the ages of intrusion and the orebody from the Tongjiangling deposit are almost identical with other typical magmatic intrusions and deposits in the Jiujiang- Ruichang metallogenic belt, and Tongling, Anqing and part of southeast Hubei in the Middle and Lower Yangtze River metallogenic belt. They belong to part of the Late Jurassic- Early Cretaceous polymetallic metallogenic events in the Middle and Lower Yangtze River metallogenic belt.