This paper reconstructed geothermal history of the Jiyang depression using apatite fission track and vitrinite reflectance model. The result indicates that in the Cenozoic, geothermal gradient in the Jiyang depression decreased gradually, with a high magnitude of decreasing in the Eogene than that in the Neogene. Meanwhile, there existed distinct differences of geothermal evolution between each sags at the Jiyang depression and the difference between sags was more obvious especially after the Dongying movement at the late of the Eogene. Based on restoration of the geothermal evolution of each sag, the Dongying sag had a highest geothermal temperature, followed by the Zhanhua sag, Huimin sag and Chezhen sag. The evolution of source rocks was closely related to ancient geothermal field. The higher geothermal gradient was, the shallower the depth of source rocks was, and the earlier the time was.