The quantitative study of the genetic mechanism of geothermal anomalies in sedimentary basins has important theoretical and practical significance for understanding the difference between heat-conduction and heat-focusing in the shallow basin and guiding the exploration of low-medium temperature geothermal resources.The Xianxian geothermal field, Hebei Province, as a typical low-medium temperature conduction geothermal resource area,developed the carbonate-bedrock geothermal reservoir of the Wumishan Formation of Jixian system(Jxw) under the Cenozoic cover of 1300~1600 m, and the wellhead water temperature of most wells in the development zone is as high as 90~95℃. Herein based on the seismic profile across the Xianxian uplift and adjacent areas, we use 2D finiteelement numerical modeling to quantitatively and semi-quantitatively investigate the difference between heat-conduction and heat-focusing in the Xianxian uplift and adjacent zone, then briefly describethe guiding significance for geothermal exploration. Our results show thatthe geothermal anomaly in the cover layer of the Xianxian uplift resulted from rapid heat transfer in the bedrock and progressive heat accumulation in the cover-rock caused by the high thermal-conductivity of the Jxw bedrock; and that the layer temperature at the top of the Jxwgeothermal reservoir in the Xianxian uplift is at least ~20℃ higher than that of the same depth strata in the Raoyang Sag, which is closely related to the bedrock uplift amplitude of nearly 3600 m. The temperature distribution in the Xianxian uplift has the characteristics of "an asymmetric mirror-reflection " structure in the longitudinal direction, and the average geothermal gradient of the caprock section is about three times that of the geothermal reservoir section, which indicates that the more "enriched" the positive geothermal anomaly in the shallow caprock section is, the more "deficit" the negative geothermal anomaly in the deep bedrock geothermal reservoir section is.The "homogenization depth of bedrock with high thermal-conductivity" represents the position of the heat conduction equilibrium line with the same average geothermal gradient between in the bedrock uplift belt with in the adjacent depressionbelts. The bedrock uplift zone under effective cover is a favorable zone for geothermal exploration;the depth of 500~800 m below the top of the geothermal reservoir in the uplift zone is the sweet section of shallow geothermal development. However, the deep geothermal exploration for the high-temperature reservoir below the "high conductivity homogenization depth" needs to avoid the bedrock uplift zone, but to select the favorable facies belt of the low convex belts or the depression belts in the basin.