Remote sensing (RS) work is difficult in the exploration of underground brine in the Salt Lake area because of concealed area in Salt Lake. The Mahai Salt Lake is an important potash forming salt lake in the Qaidam basin, China. The mineral deposit in the Mahai Salt Lake is the main ore controlling structure. In this paper, optical RS false color images and Radar were used to interpret the structures, including LANDSAT ETM and PALSAR data. Three primary structures and several secondary structures were identified and tectonic stress analysis was undertaken. Two first order compressive structures play the role of blocking water, and one first order tensile structure was considered for conducting water. Finally, two potential remote sensing prediction targets are delineated based on the analysis of known brine deposits, superficial porosity and potassium content.