Volcanic edifices are the source of all volcanic rocks and the space where most volcanic rocks and volcanic facies occur. They are the center of geological survey and research in continental volcanic rock areas. In this paper, we select the southwestern part of the Huanggangliang volcanic tectonic uplift in the Great Xing’an Range, through the establishment of volcanic activity sequence in the typical volcanic institutions and the determination of the relationship between different volcanic institutions, the volcanic structure framework in the area is restored and the volcanic process is traced back. The study reveals that the southwest part of Huanggangliang volcanic structural uplift consists of two volcanic uplifts, three caldera, one tuff ring and several small craters, which are juxtaposed, overlapped, cut or covered, forming a complex volcanic structural style. Volcanic activity in the area can be roughly divided into three stages: early, peak and late stages. Different stages have their own characteristics in volcanism, types of volcanic institutions and the main lithology. The early volcanism mainly formed the Wayaogou volcanic uplift, and the overall intensity of volcanic activity was medium low except for the eruption of certain intensity in the initial stage. The products formed are mainly overflow facies andesite and volcanic neck facies andesite porphyry; the peak volcanism was mainly characterized by large- scale eruption and collapse after strong eruption to form a number of calderas; the late volcanism is mainly manifested as boiling- overflow, extrusion, intrusion, forming Huanggangliang volcano- extrusion uplift, the intensity of volcanic activity is the weakest of the three phases. The SHRIMP zircon U- Pb ages of the third- stage volcanism products are 143.7±1.5 Ma, 140.1±1.4 Ma and 141.1±1.0 Ma respectively, which are very close within the error range, indicating that the volcanic activity in the southwest part of Huanggangliang volcanic tectonic uplift lasted for a very short time, and its formation age corresponds to the early Cretaceous Berriasian represented by the International Geological year, and some of them may last until the early Valanginian. Regional comparison shows that the late Mesozoic volcanic activity in the southern part of the Great Xing’an Range mainly includes two episodes, with peaks of ~156 Ma and ~132 Ma respectively, with a relatively quiet period of about 10 Ma in the middle. The Huanggangliang volcanic tectonic uplift formed after the quiet period, and the volcanic activity was reactivated. There are different age spectra of volcanic activity in the southern and northern parts of the Great Xing’an Range, suggesting that there are differences in the dynamic mechanism of volcanism between the two parts. The former is comparable to the late Mesozoic volcanic activity on the northern margin of North China, which may be related to the subduction of the paleo- Pacific plate and subsequent retreat of the subducted slab, while the latter may be related to the closure of the Okhotsk Ocean.