The Yiliping salt lake in the Qaidam basin are characterised by liquid lithium deposits of high economic value. This studys aims to clarify the distribution of deep brine in this lake and to estimate the brineenriched area in terms of the spatial distribution and physical characteristics of brine reservoir, thus providing a basis for future brine exploitation. The study area is located in the depocenter of the Yiliping salt lake since the end of late Pleistocene. The related sediments are mainly characterized by the shallow lake facies comprising of silt and clayey silt and the salt lake facies comprising of silt and claybearing halites. The reservoir of Lienriched brine in the Yiliping salt lake is stratigraphically composed of upper and lower halite layer with clayey silt sandwichedbetween them. The shallow lake facies mainly occur in the north, and transform southward to saline lakefacies with the thickest halite sediments in the southeast. By integrated analysis of reservoirs thickness, porosity and specific yield, we concluded that the highquality reservoirs including both the porosity and intercrystalline type in the Ⅱ brine seam are located to the east of the study area and can serve as the target area for the future exploitation of brine resources.