The Tangjiagou gold deposit is a quartz vein type deposit in the Muping- Rushan metallogenic belt, Jiaodong Peninsula. The orebody occurs in the Kunyushan rock mass near the contact zone between the Kunyushan monzogranite and the Jingshan Group metamorphic rock of the Paleoproterozoic, and is controlled by the Tangjiagou fault and its NE secondary faults. The orebodies are distributed in equidistant bead- like pattern and characterized by branching and recombination as well as expansion and pinch- out. As measuredby zircon LA- ICP- MS U- Pb method, the Kunyushan monzogranite was formed at 157. 57±0. 82 Ma. Monazite in quartz vein bearing Au of Tangjiagou gold deposit was formed at 122. 1±2. 8 Ma, which indicates the metallogenic epoch. Combined with previous data, it is proposed that the Kunyushan monzograniteare unrelated to gold deposits and belong to tectonomagmatic activity before mineralization, which formed in the partial melting of crust at the Continental compressional collision environment. The Paleo- Pacific Plate subducted Eurasian Plate in early Cretaceous Epoch, the structural system transforming from compression to extension and the crust and mantle interaction formed mixed magma. The activities were associated with gold deposits of the Muping- Rushan metallogenic belt and belong to tectonomagmatic activity in mineralization, of which the metallogenic Epoch occurred between 117~122 Ma. The lithospheric thinning occurred strongly in Jiaodong areas between 110~120 Ma, the crust and mantle mixed magma formed the Sanfoshan rocks, which are unrelated to gold deposits.