|Abstract:The Taiyanggou molybdenum deposit is located in eastern Hebei Province. Intrusions exposed in this deposit are granite porphyry and biotite monzogranite. The ore bodies mainly occur as lenticles and veins in granite porphyry and at the contact zone between granite and wall rocks.．This study reports zircon U-Pb dating, whole rock geochemistry, the molybdenite Re-Os isotopic age and S, Pb isotopic analyses, which is hepful to determine the diagenetic and metallogenic epoch, and to discuss the genesis and metallogenic process of the Taiyanggou molybdenum deposit. The weighted mean 206Pb/208U ages of the granite porphyry and biotite monzogranite are 154.8±1.5Ma and 156.5±1.2Ma, respectively. Re-Os model age weighted average of molybdenite is 155.79±0.93Ma that obtained by Re-Os isotope dating, which is within the margin of error of zircon U-Pb ages, indicated they are the product of the late Jurassic tectonic-magmatic activity. Geochemical characteristics show that the granites have high silicon, high alkali, and belong to high-K calc-alkaline series and highly differentiated type I granite, with enrichment of large ion lithophile elements (LREE, Rb, Sr, Ba) and depletion of high field strength elements (HREE, Nb, Ta, Ti). According to the analysis of S and Pb isotopes, the composition distribution of S isotope is relatively concentrated, the δ34Spyrite values are all positive (1.3‰~1.8‰, average of 1.53‰). The composition of Pb isotope is uniform (206Pb/204Pb values of 16.76~17.44, 207Pb/204Pb values of 15.28~15.43, 208Pb/204Pb values of 36.64~37.46), indicating that the metallogenic materials mainly derived from the melting of the lower crust materials mixed with the mantle. Combined with the characteristics of petrology, chronology, geochemistry and S, Pb isotopes, it is suggested that the Taiyanggou molybdenum deposit belongs to porphyry molybdenum deposit. The crust-mantle interaction caused by the subduction of the late Jurassic Pacific plate induce partial remelting of the lower crust, so as to enrich large numbers of Mo elements, and finally emplacement and sediment formed ore deposit.