In order to realize the effective investigation of geothermal resources in WulianJuxian section of Yishu fault zone, firstly, wedetermines that there are three geothermal anomalies in the investigated area, such asGuanshuaiBeidian, Donggoutou and Zhaojiage Lake, with shallow temperature measurement as the main method and combined resistivity profile measurement as the supplement, and analyses their thermal storage models. Secondly, the hydrochemical characteristics of the anomalous area are measured and evaluated. Finally, the geothermal reserves in the geothermal anomalous area are calculated. Water quality measurement and evaluation show that the geothermal anomaly area in the investigated area contains a variety of trace elements which are beneficial to human health, and it is an important geothermal water with physical and health value, which can be used for bathing and recuperation purposes besides heating. The calculation results of geothermal reserves show that three abnormal zones of GuanshuaiBeidian, Donggoutou and Zhaojiage Lake can produce heat equivalent to 747000, 104000 and 306800 tons of standard coal, respectively, and the heat storage in the abnormal zones is abundant.This provides numerical suggestions for the rational and sustainable exploitation and utilization of geothermal resources in the investigated areas, and has a certain reference value for the exploitation and utilization of geothermal resources in other regions of China.