In order to explore the application of the headspace gashydrocarbon technology in gas hydrates geochemical exploration in land permafrost regions, the known natural gas hydrate mining area of Qilian Muli and the unknown Hala Lake are chosen as the test areas. The test indices include soil top air, soil acid solution hydrocarbon, debris roof air logging and methane carbon isotope. The research shows that the methane as the main component of the headspace gas hydrocarbon above the known natural gas hydrate mining area of Qilian Muli is of high percentage, significantly higher than the conventional oil basins, and 90. 6 percent of C 1 content is above 78%. In the plane, there is an obvious anomaly of soil headspace gas methane above the mine, and on the section, there is “frontal halo” anomalous characteristics above the stable zone of the hydrate, the spatial distribution of which has close relation with Qilian mountain hydrate mineral spread distribution. The surface oil- gas geochemical anomaly is of pyrolysis origin based on the judgment of methane carbon isotopes and hydrocarbons, the same origin as the gas hydrate of Qilian mountain permafrost region. There are no obvious characteristics of headspace gashydrocarbon anomaly in the Hala Lake test area where natural gas hydrate is not discovered. The test result of geochemical exploration techniques of natural gas hydrates in the land area of permafrost region indicates that the technology can be used to determine the genetic type of hydrate, as well as the range of hydrate deposits.