The Keke gabbro, located in the southeast side at the intersection of Ertix and Koktokay and Ertai faults, South Altay, is one concealed intrusion discovered in recent exploration. In this study, we performed detailed analysis of geological characteristics, geochronology and geochemistry of the Keke gabbro. The results show that the SIMS U- Pb age of zircons from the Keke gabbro is ca 291 Ma, suggesting an age of Early Permian. The Keke gabbro exhibits low SiO2 (46. 14%~52. 53%) and MgO (3%~7. 68%) contents, with low La/Sm (2. 56~4. 10) and high (Gd/Yb)N ratios (1. 12~1. 61), as well as enrichment of LILE (K, Rb and Pb), and depletion of HFSE (Nb and Ta). Those geochemical characteristics indicate that the magma of the Keke gabbro resulted from partial melting of the oxidized replacement mantle due to subduction, weakly contaminated by crustal materials during its emplacement. Combined with geological and geochemical features, the Permian Keke gabbro in the Altay region formed in extensional tectonic setting, with emplacement of magma controlled by the Ertix strike slipping. Therefore, the gabbro is the important component of the Permian mafic magmatic rocks widely developed in the northern Xinjiang region.