The extensive magmatism and explosive mineralization occurred in the Jiaodong terrane in Late Mesozoic. In order to investigate the age of magmatic activity and its impact for mineralization, we carried out zircon U- Pb isotopic dating for samples from Xingjiashan molybdenum- tungsten deposit, Xiangkuang lead- zinc deposit and Wangjiazhuang copper deposit, based on comprehensive analysis of Late Mesozoic granitoid and mineralization in the Jiaodong terrane. The dating yields the zircon SHRIMP U- Pb isotopic age of 159. 3±1. 6 Ma and 130. 4±1. 2 Ma respectively for porphyritic granite in Xinffushan and granodiorite porphyry in Xiangkuang, and 116. 1±5. 1 Ma and 119. 8±1. 8 Ma for quartz diorite porphyrite in Yanghushan. Therefore three stages of magmatism and relative metallogenic events have been determined. Age of residual Precambrian zircons was also obtained for the Late Jurassic granitoid: 3548±12Ma, 2472. 9~2400Ma and 2192~1725Ma, which indicate that the Late Jurassic granitoid derived from recycling of the Precambrian crystalline basement. 3548±12Ma is the oldest one obtained so far, indicating the existence of early Paleoarchean ancient crystalline basement in the Jiaodong area. Comprehensive analyses suggest that the magmatism and mineralization at 160Ma± should be the products after the collision between North China craton and Yangtze craton in the compressive tectonic settings. The early Early Jurassic magmatic activity and metallogenic events of 130 Ma± are related to the subduction of the Pacific Plate and formed in a transitional environment from compressional orogeny to extensional structure. Middle to late Early Cretaceous magmatism formed in an extensional seting, likely related to destruction of the North China Craton and lithospheric thinning, which provided preferential condition for large- scale hydrothermal mineralization of Au, Ag and non-ferrous metals at 115 Ma±.