Based on outcrop, drilling data and seismic sections, and along with the study of lithology, lithofacies and facies sequence, this study defined the sequence stratigraphy of the MiddleLower Jurassic Yan’an Formation and Zhiluo Formation in the northeastern Ordos Basin. Five sequences have been recognized in the Yan’an Formation and four in the Zhiluo Formation. Each sequence is composed of low accommodation systems tract and high accommodation systems tract. Occurrence features of coal sequences and uranium ore deposits and their positions in the sequence column, it can be deduced that the coal of the Yan’an Formation occurs mainly in peat swamp environment of delta plain and the uranium of the Lower Zhiluo Formation occurs mainly in braid river deposit, which respectively represent the high accommodation systems tract and low accommodation systems tract, according to the characteristics and the position in sequence stratigraphic framework of CoalUranium distribution. In combination to geological, geochemical and paleontological data, the paper also discussed restriction of paleclimate and structure on coaluranium mineralization.