To study themigration kinetics of uranium driven by dissolved ferric iron in acid solution, a group of leaching tests on the sandstonetype uranium ore taken from the Yili Basin had been carried out with sulfuric acid solution containing different contents of ferric iron. Results show that uranium, oxidized by ferric iron, can migrate from ore to the solution within 10 hours. The migration rate declines rapidly so that it makes uranium dissolution process gets to an equilibrium stage. The rate of uranium dissolution positively correlates with that of the transformation between ferric iron and ferrous ironas exponential functions. While the transformation rate of ferric iron to ferrous iron approaches zero, the uranium oxidation process stops and then leads to an uranium dissolution equilibrium. It also shows that ferric iron concentration of 2g/L is sufficient to induce a strong dissolution of uranium migration from ore. The increasing of the solution acidity weakens the relationship between uranium dissolution rate and Fe3+conversion rate. However, when acidity changes from 2g/L to 4g/L (pH value of 1.65~1.33), the uranium leaching effect does not change significantly. So, the solution with Fe3+concentration of 2g/L and the acidity of 2g/L (pH value of 1.65) is economical and effective for uranium leaching.