South China is an important polymetallic metallogenic region for tungsten, tin, molybdenum, bismuth, uranium, lead, zinc, and rare earth elements. Recently available chronological data demonstrate that the aforementioned mineral resources occurred intensively in the Late Jurassic (165~150 Ma). Field and experimental observations indicate that these granites can be divided into three series based on degrees of differentiation and fractionation: low fractionated, highly fractionated, and cumulus crystal granites. Existing research results have shown that metallogenesis of W, Sn, Nb, Ta, Li and B, etc are closely related to highly fractionated granite. Therefore, marker establishment of mineral and whole rock geochemistry of these deposits related to highly fractionated granite will be conductive to understanding the mineralization potential in heavily vegetationcovered and strongly weathered areas as well as poorly investigated rock masses. Hetain granitic pluton in Changting county of Fujian province is poorly exposed, with most under the thick weathered layer and covered by thick vegetation. But the several prospects of Sn, W, Pb and Zn have been discovered occurring in the rock masses. This study shows that the zircon UPb age, garnet and wholerock geochemical features of the Hetian pluton are highly similar to those of the secondstage granite in Xihuashan of Jiangxi province. It can be inferred that the Hetian rock mass is of metallogenetic potential for W and Sn superlarge ore deposits. In addition, during the continuous evolution process of granite into high fractionation stage, some elements ratios (such as Rb/Sr, Zr/Hf, and Nb) can be used as parameters to weight degree of crystallization fractionation. When melts reach to interaction stage of melt and fluid, the wholerock zircon content and Zr/Hf ratio of the Xihuashan and Hetian granitic masses will change at Zr=50×10-6 and Zr/Hf=15. Meanwhile, compared with garnet in poorly metallgoenic granite, Sn, Y and Yb contents in metallogenic granite increase distinctly, likely two to ten times higher. Therefore, trace elements features of the garnet from the highly fractionated granite can likely serve as one of the key prospecting markers.