The spatial and temporal distribution, sources and petrogenesis of the massive diverse early Paleozoic magmatite in the South Altyn Tagh, are helpful to comprehensive understanding the geodynamic processes of oceanland transition, continental deep subduction, continantal slab breakoff during the collisional orogeny. In this paper, we come to the conclusion that tectonic magmatic evolution of the early Paleozoic south Altyn Tagh should be divided into four stages according to the rock types, ages and geochemistry of these magmatic associations: (1) >500Ma, the stage of ocean ridge spreading and slab subduction, the magmatic rocks are characterized by E-MORB、N-MORB and Otype adakites; (2) 497~472Ma, the stage of deep subduction of continental crust during continental collision, the magmatic rocks that consist of I and Stypes, and Ctype adakites, were products of the high press partial melting of arenaceous rocks in upper crust or basalt in lower crust; (3) 469~445Ma, the stage of primary postcollision setting, basic ultrabasic rock being characterized by OIB and IS types granites are composed of bimodal magmatite relating continantal slab uplifting, the former formed within intracontinental rift environment, the latter with low/high Sr and low Sr/Y ratios (high Sr and low Y, few), originated from partial melting of upper cruslt in the condition of reducing stress; (4) 424~385Ma, the stage of postcollision setting, Atype magmatite with high Y and low Sr should be the productions of mudstones and sandstones partial melting in upper crust at high temperature and low pressure. According to magmatic activity and tectonic evolution, the early Paleozoic tectonic evolution models of South Altyn Tagh are proposed.