The North Qaidam was an Early Paleozoic orogenic belt which was formed from deep subduction of continental crust. The U-Pb zircon ages reveal that most of the protolith ages of HPM/UHPM rocks in the North Qaidam are older than 750Ma, and the protolith belong to continental crust type. But the protolith age of coesite-bearing eclogite from Shaliuhe section in Dulan area is 516Ma, and the protolith belong to oceanic crust type, suggesting the existence of deep subduction of oceanic crust prior to the continental subduction in the North Qaidam. This paper focuses on the progress of petrology, geochronology, geochemistry and isotope geochemistry studies of the evolution about the Neoproterozoic-Early Paleozoic ocean in the North Qaidam, suggesting a continental breakup event occurred during 700~850Ma in this area, which could be related with the breakup of Rodinia, then a Neoproterozoic-Early Paleozoic ocean appears to have developed between Qaidam and Olongbuluck blocks during 535~700Ma on this basis, which was then subducted during 460~535Ma, and disappeared during 450~460Ma at last. It is of great importance to know the evolution of the HP/UHP belt in the North Qaidam.