Based on the study of the structural deformation,through strike-dip surveying of field outcropped conjugate shear joints and adopt mathematical statistics to match by stages, combining previous research achievements.and carried out the study of Dazhou volcanic faulted basin paleo-tectonic stress field and the relationship of uranium mineralization. Summed up four main tectonic stress stages: the former Cretaceous tectonic period、Moshishan tectonic period、Qujiang tectonic period、Eocene-Oligocene tectonic period, discussed the control role of the various periods on uranium mineralization, pointed out the latter three tectonic stress stages play a main part in uranium mineralization, tectonic stress field in Moshishan tectonic period prepared ore storage space,tectonic stress field in Qujiang tectonic period prepared ore transmitting space , tectonic stress field in Eocene-Oligocene tectonic period destroyed and transformed the formed ore deposits.