The biotite adamellite intruding in Proterozoic metamorphic basement of the eastern part of the Kuche depression belongs to K-high calc-alkaline igneous rocks, and it is characterizes by SiO2-rich, alkaline-rich, K-high, low-TiO2 and metaluminous rock with A/CNK= 0.92~1.15. The adamellite enriches in elements such as Rb, Th, K, Nd, Zr, Y and Tb, and depletes in elements such as Ba, U, Nb, Ta, Sr, P, Sm, Ti with negative Eu anomaly（Eu=0.06~0.11）. Geochemical features of the granitoid rocks reveal its derivation from partial melting of middle-lower crust. In situ zircon U-Pb LA-ICP-MS dating on the magmatic genetic zircon yields an age of 646.5±3.9Ma, representing the emplacement age of the granites. Combined with regional tectonic analysis, it is concluded that the Neo-proterozoic magmatism is resulted from the response of basement of Tarim craton to the Rodinia splitting.