A series of manganese deposits of Datangpo Formation were discovered in east Guizhou Province and west Hunan Province, China, it is shown that Datangpo Stage, Neoproterozoic is an important manganese mineralization period. Manganese deposit was discovered in Gaozeng, Congjiang County, southeastern Guizhou recent, it is shown that manganese mineralization in Datangpo Stage is widely. On the basis of sediment character, mineral assemblage and geochemical character of manganese deposit in Datangpo Formation at Gaozeng, Congjiang County, the manganese deposit was suggested hydrothermal mineralization, major proofs as flowing: (1) rich in Cu、Zn、Ni、Nb、Co、Mo、As、Sb、Sr、Ba、V、Ga、Ag、Th、Ｕ, especially richest in Pb, Co, W. (2) black thick manganese, laminated manganese and white tuff fell in the hydrothermal and hydrogenic fields of U-Th related map, Cr-Zr related map and Co/Zn-(Co+Ni+Cu) related map. The REE distribution model of the black thick manganese, laminated manganese and white tuff is similar to those of hydrothermal fluid exhalation sediment of Bikou Group. (3) tuff, siliceous rock, manganese and black carbonaceous shale assemblage belong to hydrothermal fluid exhalation sediment. Sum up, Gaozeng manganese deposit is of hydrothermal fluid exhalation sediment, and the manganese deposit was controlled by synchronous fault, therefore, synchronous fault belt in Datangpo Stage is potential mineralization region of manganese deposit.