To discern the material sources of the Dachang tinpolymetallic deposit，this paper analyzes and compares sulfur and lead isotope data of the orebodies with different mineralization types or occurrences from the deposit. The results indicate that the orebodies with different type and occurrence originated from the same source. Sulfur isotopic evidence indicates that Zn-Pb orebodies are typical magmatic sulfur in origin, Sn orebodies in mixed origin. Change of sulfur isotopic ratios is related to ore-formed process and environment, reflecting that there was a foreign components from country rock involving mineralization during the movement of deepderived oreforming fluid from low to upper. Lead isotope data indicate that lead originates mainly from the crustderived magmatism but doesn't exclude involvement of Pb from the igneous intrusion.