This article presents the precise chronology study on the acid intrusive rocks and mineralization in the Lame ore deposit of Dachang ore field in Guangxi using different isotopic datings. SHRIMP UPb insitu zircon age of phenocrystbearing biotite granite is 94±4Ma (with 95% credibility), whole rock RbSr isochrone age of that is 98.6±1.9Ma (with 95% credibility), and quartz RbSr isochrone age of zinccopper ore during skarn mineralization is 98.6±6Ma (with 95% credibility). These results indicate that mineralization age of the Lame zinccopper ore deposit is consistent to the lithogenesis age of correlated plutons, both at the late stage of Late Cretaceous Epoch.