Hua’nan area (South China) is one of the key bases for nonferrous metal mining in China. It has boasted a welldeveloped mining industry, but also nortious for a number of crisis mines. Exploration of most deposits was completed about 20 years ago, producing abundant research result. Exploring new deposits has become more and more difficult. Therefore, it is the high time to start the deep prospecting in the Hua'nan area, which has drawn a wide attention from the national and local governments and enterprises. It is very necessary to further study mass source, classification of ore deposits, partition of metallogenic belts and changes at a certain depth (such as 3000m), to clearly determinde target areas on surface and blind orebodies at depth, and to fasten the middledeep drilling exploration (at 1000~3000m) and the related measure technology. This study focuses on evaluate potential of mineral resources by using three principles“conservation of mass”, “conservation of energy”, and “infinity of spacetime with order”.