The component and carbon isotope of natural gas are mainly controlled by the type of organic matter and maturity. But, more and more examples indicate that the accumulation process of natural gas also control the component and carbon isotope of natural gas. Although the natural gas in the different structural belt of the Kuqa foreland basin has the same original source, mainly generated by Jurassic source rock and less Triassic source rock, the natural gas in the overthrust belt, slope zone and forebulge zone of the Kuqa foreland basin was obviously different in component, content of dry and wet gas and carbon isotope. The accumulation history of hydrocarbon in the Kuqa foreland basin was that the early accumulated hydrocarbon was destructed and then hydrocarbon generated in late stage accumulated. The paper indicated that the accumulation process of hydrocarbon obviously controlled the component and carbon isotope of natural gas in the different structural belt of the Kuqa foreland basin.