The East Tianshan, located in northeastern Xinjiang and in the middle of Central Asia, has many tectono-magmatic belts connecting with those in Central Asia and is rich in metal deposits. Compressional collision be-tween Kazakhstan and the Tarim palaeoplate provided excellent conditions for mineralization and consequently a large number of endogentic metallic deposits were formed. The East Tianshan is one of the very important met-allogenic belts in China, the discovery of the Tuwu-Yandong large porphyry copper deposit is the most impor-tant breakthrough in mineral exploration in Xinjiang, and even in the whole China. It has good ore potentials. Based on the systematical records of metallogenic geological settings, characteristics of representative ore de-posits and late Palaeozoic geodynamic evolutions, four metallogenic series and seven mineralization types are rec-ognized. Late Palaeozoic crustal evolution went through the extension stage, compression stage, collision stage, post-collisional extension stage, strike-slip stage and partial extension stage, and each stage is accompanied by a type of ore deposit or a metallogenic series.